Pontine haemorrhage due to chondrosarcoma of the skull base.

Chondrosarcoma of cranial vault: case report and review of literature

Chondrosarcoma is a rare malignant cartilage forming tumour usually arising from long bones and rarely seen in cranium. In cranium it is seen to commonly arises from skull base with skull vault being a highly unusual site. We report a case of a 30-year female presenting with complaints of headache for 6 months found to have a large chondrosarcoma in right fronto-parietal region which is an extr...

Skull Base Chondrosarcoma: Is there a Role of Endoscopic Excision?

Skull base chondrosarcomas are rare and account for approximately 0.15% of all intracranial tumors. Management of these tumors is challenging because of their potential to recur, and their proximity to vital structures such as major vessels and cranial nerves. We describe five patients with chondrosarcoma of the skull base who were managed at our institute between January 2002 and December

Feasibility of proton beam therapy for chordoma and chondrosarcoma of the skull base.

We explored the general feasibility of proton beam therapy for chordoma and chondrosarcoma of the skull base. Clinical records and treatment-planning data of patients with the pathological diagnosis of chordoma or chondrosarcoma were examined. Proton beam therapy was administered for gross tumor mass as well as microscopic residual disease after surgery. The prescribed dose was determined to ma...

Clinicopathological significance of p16, cyclin D1, Rb and MIB-1 levels in skull base chordoma and chondrosarcoma

Objective To investigate the expression of p16, cyclin D1, retinoblastoma tumor suppressor protein (Rb) and MIB-1 in skull base chordoma and chondrosarcoma tissues, and to determine the clinicopathological significance of the above indexes in these diseases. Methods A total of 100 skull base chordoma, 30 chondrosarcoma, and 20 normal cartilage tissue samples were analyzed by immunohistochemis...

MRI characterization of skull base chordoma and chondrosarcoma in a patient collective referred for proton radiation therapy